Calciprotein Particles Induce Endothelial Dysfunction by Impairing Endothelial Nitric Oxide Metabolism.
Lian FeenstraAnton G KutikhinDaria K ShishkovaHendrik BuikemaLara ZeperArno R BourgonjeGuido KrenningJan-Luuk HillebrandsPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
CPPs cause endothelial cell dysfunction by impairing nitric oxide metabolism and generating oxidative stress. Our findings provide new evidence for direct effects of CPPs on ECs and pathways involved.