Multimodal analysis of gene expression from postmortem brains and blood identifies synaptic vesicle trafficking genes to be associated with Parkinson's disease.

Xiaoya GaoZifeng HuangCailing FengChaohao GuanRuidong LiHaiting XieJian ChenMingchun LiRongfang QueBin DengPeihua CaoMengyan LiJianjun LuYihong HuangMinzi LiWeihong YangXiaohua YangChunyan WenXiaomei LiangQin YangYin-Xia ChaoLing-Ling ChanMidori A YenariKunlin JinK Ray ChaudhuriJing ZhangEng-King TanDennis Qing Wang

Published in: Briefings in bioinformatics (2021)

This study highlights that SVT genes, especially SYNJ1, may be promising markers in discriminating PD from HCs and PPS.

Keyphrases

genome wide
gene expression
dna methylation
bioinformatics analysis
genome wide identification
genome wide analysis
chronic pain
transcription factor