Comparison of Six Automated Immunoassays With Isotope-Diluted Liquid Chromatography-Tandem Mass Spectrometry for Total Thyroxine Measurement.

Songlin YuWeiyan ZhouXinqi ChengQinghui MengHonglei LiLi'an HouJun LuShaowei XieQian ChengChuanbao ZhangLing Qiu

Published in: Annals of laboratory medicine (2019)

Though all immunoassays correlated strongly with ID-LC-MS/MS, most did not meet the minimum clinical requirement. Laboratories and immunoassay manufacturers must be aware of these limitations.

Keyphrases

liquid chromatography tandem mass spectrometry
simultaneous determination
ms ms
solid phase extraction
machine learning
deep learning
high throughput
sensitive detection
gas chromatography
tandem mass spectrometry
label free
high resolution