Elevated serum uric acid is a facilitating mechanism for insulin resistance mediated accumulation of visceral adipose tissue.

Luisa Fernandez-Chirino Neftalí Eduardo Antonio-Villa Carlos A Fermín-Martínez Alejandro Márquez-Salinas Enrique C Guerra Arsenio Vargas-Vázquez Paloma Almeda-Valdes Donaji Veronica Gomez-VelascoTania L Viveros-RuizRosalba Rojas Carlos Alberto Aguilar-Salinas Omar Yaxmehen Bello-Chavolla

Published in: Clinical endocrinology (2022)

Elevated SUA acts as a mediator inside the bidirectional relationship between IR and VAT accumulation and these observations could be applicable at a phenotype scale.

Keyphrases

insulin resistance
uric acid
metabolic syndrome
adipose tissue
high fat diet
polycystic ovary syndrome
skeletal muscle
high fat diet induced
type diabetes
glycemic control