Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis.

Patricia Costa-ReisKelly MaurerMichelle A PetriDaniella Levy ErezXue ZhaoWalter FaigJon BurnhamKathleen O'NeilMarisa S Klein-GitelmanEmily von SchevenLaura Eve Schanberg Kathleen E Sullivan

Published in: Lupus science & medicine (2022)

All three biomarkers were associated with new onset proteinuria and increased VCAM-1 may predict impending proteinuria. These biomarkers provide potential non-invasive measures for monitoring that may be more sensitive to impending flare than conventional measures.

Keyphrases

intensive care unit
emergency department
cell adhesion
risk assessment