Ocular Pharmacokinetics of 25-Hydroxyvitamin D3 After Weekly Supplementation in Rabbits Using Ultra Performance Liquid Chromatography-Tandem Mass Spectrometer.
Archit KumarMini P SinghTripti RungtaAjay PatialSavita Verma AttriBikash MedhiRadha Kanta RathoPublished in: European journal of drug metabolism and pharmacokinetics (2019)
The oral supplementation of 25D3 was found to significantly increase 25D3 levels in aqueous humor; however, the time required to achieve 25D3 concentration in aqueous humor was higher as compared to that in serum. Therefore, weekly oral supplementation of 25D3 may have a beneficial role in ocular diseases.