Augmentation strategies for clozapine refractory schizophrenia: A systematic review and meta-analysis.

Dan J SiskindMichael LeeArul RavindranQichen ZhangEvelyn MaBalaji MotamarriMeshary Khaled N Alotiby

Published in: The Australian and New Zealand journal of psychiatry (2018)

On the basis of the limited data available, the best evidence is for the use of aripiprazole, fluoxetine and sodium valproate as augmentation agents for total psychosis symptoms and memantine for negative symptoms. However, these conclusions are tempered by generally short follow-up periods and poor study quality.

Keyphrases

bipolar disorder
soft tissue
sleep quality
electronic health record
quality improvement
machine learning
depressive symptoms
deep learning
artificial intelligence