Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity.
Margitta WormAikaterina AlexiouAndrea BauerRegina TreudlerGerda WurptsHeinrich DickelTimo BuhlSabine MüllerAndreas JungRandolf BrehlerJoachim FluhrLudger KlimekNorbert MülleneisenWolfgang PfütznerUlrike RaapStefani RoeselerSandra SchuhHartmut TimmermannGuido HeineBettina WediKnut BrockowPublished in: Allergy (2022)
Proven IgE-mediated hypersensitivity to SARS-CoV-2 vaccines is extremely rare and not increased in comparison with reported hypersensitivity to other vaccines. The value of skin tests is unclear and nonspecific reactions, in particular when intradermal testing is applied, should be considered.