Monocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligands.
Darrell PillingElkin Galvis-CarvajalTejas R KarhadkarNehemiah CoxRichard H GomerPublished in: BMC immunology (2017)
These results suggest that the presence of pentraxins and their ligands regulate macrophage differentiation in the blood and tissues, and that CRP may be a potent inducer of the anti-inflammatory cytokine IL-10.