Risk factors for thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype.
M M T J BroekmanM J H CoenenG J WantenC J van MarrewijkO H KlungelA L M VerbeekP M HooymansH-J GuchelaarH SchefferL J J DerijksDennis R WongD J de JongPublished in: Alimentary pharmacology & therapeutics (2017)
Low baseline WBC count and mercaptopurine, due to a relatively higher dose, were risk factors for thiopurine-induced leucopenia in patients without a TPMT variant.