Colchicine treatment increases the risk for fetal chromosomal aberrations-an observational study and systematic literature review.
Amihood SingerJulia Grinshpun-CohenSagi-Dain LenaPublished in: Rheumatology (Oxford, England) (2021)
The results of our observational study support the concern that colchicine treatment is associated with increased risk for fetal chromosomal aberrations; however, the absolute risk is relatively low (one in 151 pregnancies). This information should be taken into account when considering invasive testing in such pregnancies.