Pravastatin attenuates atherosclerosis after myocardial infarction by inhibiting inflammatory Ly6Chigh monocytosis in apolipoprotein E knockout mice.

Yufei ChenHongqi ZhangLiang HuHaiming ShiXiaojin LiuJianguo JiaShengjia SunYang OuXinping LuoGuomin ZhouWei Shen

Published in: The Journal of international medical research (2021)

MI accelerated chronic atherosclerosis progress. Pravastatin suppressed atherosclerotic development and inhibited inflammatory monocytosis after MI in ApoE-/- mice.

Keyphrases

cardiovascular disease
oxidative stress
signaling pathway
high fat diet
skeletal muscle
adipose tissue