Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort.

Anna C Rivara Emily M Russell Jenna Colavincenzo Carlson Alysa PomerTake NaseriMuagututia Seifuiva ReupenaSamantha L MannaSatupaitea VialiRyan L MinsterDaniel E WeeksJames P DeLanyErin E KershawStephen T McGarveyNicola L Hawley

Published in: PloS one (2024)

Further research is needed to understand the effect of the A allele on fasting glucose and type 2 diabetes development. Based on our observations that other risk factors increased over time, we advocate for the continued promotion for diabetes prevention and treatment programming, and the reduction of modifiable risk factors, in this setting.

Keyphrases

blood glucose
risk factors
glycemic control
type diabetes
insulin resistance
cardiovascular disease
intellectual disability
metabolic syndrome
autism spectrum disorder
combination therapy
smoking cessation
replacement therapy