First Report of Skunk Amdoparvovirus (Species Carnivore amdoparvovirus 4 ) in Europe in a Captive Striped Skunk ( Mephitis mephitis ).

Skunk amdoparvovirus ( Carnivore amdoparvovirus 4 , SKAV) is closely related to Aleutian mink disease virus (AMDV) and circulates primarily in striped skunks ( Mephitis mephitis ) in North America. SKAV poses a threat to mustelid species due to reported isolated infections of captive American mink ( Neovison vison ) in British Columbia, Canada. We detected SKAV in a captive striped skunk in a German zoo by metagenomic sequencing. The pathological findings are dominated by lymphoplasmacellular inflammation and reveal similarities to its relative Carnivore amdoparvovirus 1 , the causative agent of Aleutian mink disease. Phylogenetic analysis of the whole genome demonstrated 94.80% nucleotide sequence identity to a sequence from Ontario, Canada. This study is the first case description of a SKAV infection outside of North America.