6-Nitrodopamine Is the Most Potent Endogenous Positive Inotropic Agent in the Isolated Rat Heart.
José Britto-JúniorLincoln Rangel Medeiros-TeixeiraAntonio Tiago LimaLetícia Costa DassowRodrigo Álvaro Brandão Lopes-MartinsRafael CamposManoel Odorico MoraesMaria Elisabete A MoraesEdson AntunesGilberto De NucciPublished in: Life (Basel, Switzerland) (2023)
6-nitrodopamine is the major catecholamine released from rat isolated ventricles. It is 1000 times more potent than dopamine and noradrenaline and is selectively blocked by atenolol, indicating that 6-ND is a main regulator of heart inotropism.