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Differentially expressed mRNAs, proteins and miRNAs associated to energy metabolism in skeletal muscle of beef cattle identified for low and high residual feed intake.

Elisa B CarvalhoMateus P GionbelliRafael T S RodriguesSarah F M BonilhaCharles J NewboldSimone E F GuimarãesWalmir SilvaLucas L VerardoFabyano F SilvaEdenio DetmannMarcio de Souza Duarte
Published in: BMC genomics (2019)
Our results show that Nellore cattle divergently identified for feed efficiency by RFI present changes in the abundance of proteins involved in energy expenditure in skeletal muscle. Moreover, our data point towards that miR-665, miR34a and miR-2899 are likely involved in controlling both 14-3-3 epsilon and HSPB1 proteins identified as differentially abundant in the skeletal muscle of RFI-High and RFI-Low Nellore cattle.
Keyphrases
  • skeletal muscle
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • insulin resistance
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • wastewater treatment
  • genome wide analysis