Optimising intravenous salbutamol in children: a phase 2 study.

Sandra WalshShan PanYucheng ShengFrank KloproggeJoe F StandingBrian J AndersonPadmanabhan Ramnarayannull null

Published in: Archives of disease in childhood (2022)

A paediatric PKPD model for salbutamol is described. An infusion of 0.5 µg/kg/min after bolus achieves effective bronchodilation. Higher rates are associated with greater tachycardia and hyperglycaemia.

Keyphrases

young adults
intensive care unit
low dose
emergency department
open label
high dose
catheter ablation
double blind
placebo controlled