Non-familial cardiomyopathies in Lebanon: exome sequencing results for five idiopathic cases.

Marwan M RefaatSylvana HassaniehJad A BalloutPatrick ZakkaMostafa HotaitAthar KhalilFadi BitarMariam ArabiSamir ArnaoutHadi SkouriAntoine AbcheeBernard Abi-SalehMaurice KhouryAndreas MassourasGeorges Nemer

Published in: BMC medical genomics (2019)

Our results unravel novel mutations in known genes implicated in cardiomyopathies in Lebanon. Changes in clinical management however, require genetic profiling of a larger cohort of patients.

Keyphrases

end stage renal disease
genome wide
ejection fraction
newly diagnosed
chronic kidney disease
single cell
copy number
prognostic factors
dna methylation
gene expression
patient reported outcomes
transcription factor
bioinformatics analysis