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Feasibility study for a randomized clinical trial of bupivacaine, lidocaine with adrenaline, or placebo wound infiltration to reduce postoperative pain after laparoscopic cholecystectomy.

A T AdenekanA A AderounmuF O WuraolaA M OwojuyigbeA O AdetoyeDmitri NepogodievL MagillA BhanguAdewale Oluseye Adisa
Published in: BJS open (2019)
Recruitment, compliance with the randomized allocation, and completion of pain outcome measures were satisfactory. This study demonstrates the feasibility of conducting a surgical RCT in a resource-limited setting. Registration number: ISRCTN 17667918 (https://www.isrctn.com).
Keyphrases
  • postoperative pain
  • double blind
  • phase iii
  • placebo controlled
  • pain management
  • chronic pain
  • open label
  • clinical trial
  • phase ii
  • spinal cord injury