Hepatoprotective effect of amifostine and WR-1065 on acetaminophen-induced liver toxicity on Wistar rats.
Hashem RasouliBibi Marjan RazaviMahboobeh Ghasemzadeh RahbardarHamid SadeghianSeyed Abbas Tabatabaee YazdiHossein Hosseinzadeh
Published in: Naunyn-Schmiedeberg's archives of pharmacology (2024)
Amifostine and WR-1065 as antioxidant and hepatoprotective compounds are effective in reducing acetaminophen-induced hepatotoxicity with a similar effect to NAC and can be administered as an adjunct in the treatment of acetaminophen overdose.