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All eyes on a phosphatase in glioma stem cells.

Robert A LindquistWilliam A Weiss
Published in: The Journal of experimental medicine (2021)
In this issue of JEM, Zhang et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20202669) identify a dependency of glioma stem cells on tyrosine phosphatase activity of EYA2 and a new role for this phosphatase at the centrosome, offering a new therapeutic approach to target mitotic activity.
Keyphrases
  • stem cells
  • protein kinase
  • cell therapy
  • optical coherence tomography
  • cell cycle
  • bone marrow
  • mesenchymal stem cells
  • cell proliferation