Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery.
Shokoufeh CheheiliSobbiAnnemieke M Peters van TonEsther M WesselinkMarjolein F LooijeJelle GerretsenWim J MorshuisArjen J C SlooterWilson F AbdoPeter PickkersMark van den BoogaardPublished in: Journal of cardiothoracic surgery (2021)
The post-operative attenuation of ex vivo-stimulated production of pro- and anti-inflammatory cytokines was comparable between patients that developed delirium and those who remained delirium-free after on-pump cardiothoracic surgery. This finding suggests that immunoparalysis is not more common in cardiothoracic surgery patients with delirium compared to those without.