Fasting and refeeding triggers specific changes in bile acid profiles and gut microbiota.

Yi ZhangHongyan QiLong WangChunyan HuAibo GaoQihan WuQiaoling WangHuibin LinBanru ChenXingyu WangShuangyuan WangHong LinWei-Qing Wang Yu-Fang BiJiqiu WangJieli LuRuixin Liu

Published in: Journal of diabetes (2023)

We characterized the BA profiles, gut microbiota, and gene expression responsible for BA biosynthesis and intestinal reabsorption to explore their rapid changes in response to food availability. Our study highlighted the rapid effect of nutrient supply on BAs and gut microbiota.

Keyphrases

gene expression
dna methylation
loop mediated isothermal amplification
insulin resistance
blood glucose
type diabetes
blood pressure
adipose tissue
skeletal muscle