Surfactant-templated zeolites for the production of active pharmaceutical intermediates.
Noemi LinaresFrancisco G CirujanoDirk E De VosJavier Garcia-MartinezPublished in: Chemical communications (Cambridge, England) (2019)
A hierarchical USY zeolite has been produced using the surfactant-templating method and used as a catalyst for the production of two important active pharmaceutical ingredients. The presence of intracrystalline mesoporosity in the zeolite results in a significant increase in both the activity (up to 30 fold increase in TOF) and reusability for Friedel-Crafts alkylation and aldol condensation steps.