Identification of Dihydrolipoamide Dehydrogenase as Potential Target of Vemurafenib-Resistant Melanoma Cells.
Claudio TabolacciDeborah GiordanoStefania RossiMartina CordellaDaniela D'ArcangeloFederica MoschellaStefania D'AtriMauro BiffoniAngelo FacchianoFrancesco FacchianoPublished in: Molecules (Basel, Switzerland) (2022)
Our proteomic and structural investigations on resistant sublines indicate that DLD may represent a novel and potent target for overcoming vemurafenib resistance in melanoma cells.