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Bioinspired artificial platelets for transfusion applications in traumatic hemorrhage.

Aditya GirishUjjal SekhonAnirban Sen Gupta
Published in: Transfusion (2019)
Among blood components, platelets (PLTs) present the toughest logistic challenges in transfusion due to limited availability, difficult portability and storage, high contamination risks, and very short shelf life (approx. 5 days). Robust research efforts are being directed to develop biologic PLTs in vitro as well as design biosynthetic and artificial PLT technologies that can potentially resolve these challenges to allow adequate availability and timely transfusion to improve survival in trauma.
Keyphrases
  • cardiac surgery
  • sickle cell disease
  • human health
  • spinal cord injury
  • rheumatoid arthritis
  • risk assessment
  • acute kidney injury
  • quality improvement
  • health risk
  • climate change
  • heavy metals
  • trauma patients