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Percutaneous closure versus medical therapy for stroke with patent foramen Ovale: a systematic review and meta-analysis.

Xin-Lin ZhangLi-Na KangLian WangBiao Xu
Published in: BMC cardiovascular disorders (2018)
In conclusion, PFO closure reduced the incidences of stroke and the composite outcome of ischemic stroke, TIA, or all-cause death, but increased risks for atrial fibrillation or atrial flutter and pulmonary embolism compared with medical therapy.
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