Identification of Core Prognosis-Related Candidate Genes in Chinese Gastric Cancer Population Based on Integrated Bioinformatics.
Mengjun LiXinhai WangJun LiuXiang MaoDongbing LiZhouyu WangYifan TangShuangjie WuPublished in: BioMed research international (2020)
A total of four genes including COL1A1, COL5A2, COL12A1, and VCAN were considered potential GC biomarkers in the Chinese population. And ECM-receptor interaction, focal adhesion, and PI3K-Akt signaling pathway were revealed to be important mechanisms of GC. Our findings provide novel insights into the occurrence and progression of GC in the Chinese population.
Keyphrases
- pi k akt
- signaling pathway
- cell cycle arrest
- cell proliferation
- gas chromatography
- bioinformatics analysis
- risk assessment
- epithelial mesenchymal transition
- induced apoptosis
- genome wide
- single cell
- high resolution
- cell death
- mass spectrometry
- pseudomonas aeruginosa
- extracellular matrix
- escherichia coli
- oxidative stress
- staphylococcus aureus
- cystic fibrosis
- drug induced