Effect of age on the diagnostic efficiency of HbA1c for diabetes in a Chinese middle-aged and elderly population: The Shanghai Changfeng Study.

Li WuHuandong LinJian GaoXiaoming LiMingfeng XiaDan WangQiqige AletengHui MaBaishen PanHuan-Dong Lin

Published in: PloS one (2017)

The diagnostic efficiency of HbA1c for diabetes decreased with aging, and this age effect was induced by the decreasing RBC count with age. HbA1c is unsuitable for diagnosing diabetes in elderly individuals because of their physiologically decreased RBC count.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
middle aged
peripheral blood
community dwelling
red blood cell
metabolic syndrome
insulin resistance
weight loss