Cisplatin exposure alters tRNA-derived small RNAs but does not affect epimutations in C. elegans.

Manon FalletRachel WilsonPeter Sarkies

Published in: BMC biology (2023)

Our work shows that epimutations are not substantially altered by cisplatin exposure but identifies transient changes in tRNA-derived small RNAs as a potential source of variation induced by genotoxic stress.

Keyphrases

genome wide
cerebral ischemia
gene expression
dna methylation
stress induced
heat stress
subarachnoid hemorrhage