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The effect of rapamycin and its analogues on age-related musculoskeletal diseases: a systematic review.

Hong LinFelipe SalechAnthony Martin LimSara VogrinGustavo Duque
Published in: Aging clinical and experimental research (2022)
Although there are studies that have evaluated the effect of rapamycin and rapalogues on MSKD in humans, the evidence supporting its use is still incipient, and the clinical implication of these results on the development of osteoporosis, sarcopenia, or osteosarcopenia has not been studied, opening an interesting field for future research.
Keyphrases
  • postmenopausal women
  • bone mineral density
  • skeletal muscle
  • current status
  • molecular docking
  • case control
  • structure activity relationship