Neurological manifestations of Erdheim-Chester Disease.
Louisa B RagsdaleKevin J O'BrienNeval OzkayaTanya LehkyAvner MeodedBernadette R GochuicoFady Hannah-ShmouniAvindra NathCamilo ToroWilliam A GahlJuvianee I Estrada-VerasRahul H DavePublished in: Annals of clinical and translational neurology (2020)
In patients with ECD, neurologic morbidity is common and contributes significantly to disability. Since neurologic symptoms can be the presenting feature of ECD and, given the mean delay in ECD diagnosis is 4.2 years, it is critical that neurologists consider of ECD and other histiocytosis in patients with inflammatory, infectious, or neoplastic-appearing white matter. Furthermore, given the broad spectrum of neurologic involvement, neurologists have an important role in a team of specialists treating ECD patients.