Targeting histone-acetyltransferase Tat-interactive protein 60 inhibits intestinal allergy.

G YangB-H ChengS-B YangZhi-Qiang LiuS-Q QiuL-T YangR-D XieX-R GengM-G LiL GaoZhi-Gang Liu Ping-Chang Yang

Published in: Allergy (2017)

Tat-interactive protein 60 (Tip60) plays an important role in the induction of IgE in B cells. Blocking Tip60 inhibits the allergic inflammation in the intestine, suggesting Tip60 inhibitor may be a potential anti-allergy drug.

Keyphrases

atopic dermatitis
protein protein
oxidative stress
dna methylation
binding protein
emergency department
cancer therapy
infectious diseases
small molecule