Differential expression of p52 and RelB proteins in the metastatic and non-metastatic groups of uveal melanoma with patient outcome.
Mithalesh Kumar SinghLata SinghKunzang ChosdolNeelam PushkerNeeru SainiRachna MeelSameer BakhshiSeema SenRachna MeelPublished in: Journal of cancer research and clinical oncology (2019)
Our data showed that non-canonical NFκB proteins were significantly higher in metastatic cases and associated with poor outcome of the patients. Furthermore, the p52 protein could be used as a potential therapeutic biomarker for metastatic cases in uveal melanoma.
Keyphrases
- squamous cell carcinoma
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- signaling pathway
- prognostic factors
- case report
- electronic health record
- immune response
- patient reported outcomes
- pi k akt
- nuclear factor
- inflammatory response
- binding protein
- toll like receptor