Association between sleep disordered breathing in early pregnancy and glucose metabolism.
Laura SanapoMargaret H BublitzAlice BaiNiharika MehtaGeralyn M MesserlianPatrick M CatalanoGhada BourjeilyPublished in: Sleep (2022)
SDB and insulin resistance are associated in early pregnancy, with a dose response association between respiratory event index severity and insulin resistance. Further studies are needed to establish if pregnant women with overweight and obesity may benefit from early SDB screening to improve glucose metabolic outcome. Clinical trials: NCT02412696, Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP) https://clinicaltrials.gov/ct2/show/NCT02412696?term=Bourjeily&draw=2&rank=2 and NCT02917876, Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy (Predictors) https://clinicaltrials.gov/ct2/show/NCT02917876?term=Bourjeily&draw=2&rank=1.
Keyphrases
- positive airway pressure
- sleep apnea
- obstructive sleep apnea
- insulin resistance
- clinical trial
- image quality
- adipose tissue
- computed tomography
- dual energy
- preterm infants
- contrast enhanced
- metabolic syndrome
- high fat diet
- polycystic ovary syndrome
- type diabetes
- gestational age
- high fat diet induced
- positron emission tomography
- pregnant women
- preterm birth
- magnetic resonance imaging
- blood glucose
- blood pressure
- pregnancy outcomes
- respiratory tract
- weight loss