Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides .
Ming-Jen ChengMing-Der WuChao-Lin ChangHsun-Shuo ChangChiou-Fung ChyuYueh-Hsiung KuoPublished in: Molecules (Basel, Switzerland) (2022)
Five new dimer compounds, namely Taiwaniacryptodimers A-E ( 1 - 5 ), were isolated from the methanol extract of the roots of Taiwania cryptomerioides . Their structures were established by mean of spectroscopic analysis and comparison of NMR data with those of known analogues. Their antifungal activities were also evaluated. Our results indicated that metabolites 1 , 2 , 4 , and 5 displayed moderate antifungal activities against Aspergillus niger , Penicillium italicum , Candida albicans , and Saccharomyces cerevisiae .