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Novel Antifungal Dimers from the Roots of Taiwania   cryptomerioides .

Ming-Jen ChengMing-Der WuChao-Lin ChangHsun-Shuo ChangChiou-Fung ChyuYueh-Hsiung Kuo
Published in: Molecules (Basel, Switzerland) (2022)
Five new dimer compounds, namely Taiwaniacryptodimers A-E ( 1 - 5 ), were isolated from the methanol extract of the roots of Taiwania   cryptomerioides . Their structures were established by mean of spectroscopic analysis and comparison of NMR data with those of known analogues. Their antifungal activities were also evaluated. Our results indicated that metabolites 1 , 2 , 4 , and 5 displayed moderate antifungal activities against Aspergillus   niger , Penicillium   italicum , Candida   albicans , and Saccharomyces   cerevisiae .
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