Impact of Efavirenz Metabolism on Loss to Care in Older HIV+ Africans.
Jessie TorgersenScarlett L BellamyBakgaki RatshaaXiaoyan HanMosepele MosepeleAthena F ZuppaMarijana VujkovicAndrew P SteenhoffGregory P BissonRobert GrossPublished in: European journal of drug metabolism and pharmacokinetics (2019)
Older age was associated with loss to care, especially among those with slow efavirenz metabolism. Understanding the relationship between older age and CYP2B6 genotype will be important to improving outcomes in an aging population initiating efavirenz-based ART in similar settings.
Keyphrases
- antiretroviral therapy
- hiv infected
- community dwelling
- human immunodeficiency virus
- hiv infected patients
- hiv positive
- middle aged
- healthcare
- hiv aids
- physical activity
- palliative care
- quality improvement
- pain management
- hepatitis c virus
- type diabetes
- health insurance
- insulin resistance
- metabolic syndrome
- skeletal muscle
- weight loss