Short NK and naïve T-cell telomere length is associated with thyroid cancer in childhood cancer survivors: A report from the Childhood Cancer Survivor Study.
Tsz-Kwong ManGeraldine AubertMelissa A RichardWanda LeJeuneElmira HaririTatiana GoltsovaAmos GaikwadYan ChenJillian WhittonWendy M LeisenringMichael A ArnoldJoseph P NegliaYutaka YasuiLeslie L RobisonGregory T ArmstrongSmita BhatiaMaria Monica J GramatgesPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)
The long-term impact of childhood cancer treatment on immune function is poorly understood. Our findings support immune function studies in larger survivor cohorts to assess long-term deficits in adaptive and innate immunity that may underlie SMN risk.