Clinical significance of STEAP1 extracellular vesicles in prostate cancer.

Karan KhannaNikki SalmondKalan S LynnHon S LeongKarla C Williams

Published in: Prostate cancer and prostatic diseases (2021)

STEAP1 is known to be enriched on the cells of the prostate with potential clinical significance in prostate cancer. Our results identify and quantitate STEAP1-positive EVs in plasma and provide rationale for a STEAP1 EV-based liquid biopsy as a diagnostic strategy in prostate cancer.

Keyphrases

prostate cancer
radical prostatectomy
induced apoptosis
clinical trial
cell cycle arrest
oxidative stress
ionic liquid
risk assessment
endoplasmic reticulum stress
cell proliferation