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Prevalence and Risk Factors for Pharmacoresistance in Children With Focal Cortical Dysplasia-Related Epilepsy.

Nathan T CohenPhat ChangXiaozhen YouAnqing ZhangKathryn A HavensChima O OluigboMatthew T WhiteheadTaha GholipourWilliam D Gaillard
Published in: Neurology (2022)
Failure of one antiseizure medication is associated with substantial risk of pharmacoresistance. These data support an operational re-definition of pharmacoresistance, for surgical planning, in FCD-related epilepsy to the failure of one antiseizure medication, and support early, potentially curative surgery to improve outcomes in this patient population.
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