Metformin use and the risk of anal intraepithelial neoplasia in type II diabetic patients.
Angela Ting-Wei HsuYa-Ching HungSandy H FangChristopher R D'AdamoArun A MavanurShane M SvobodaJoshua H WolfPublished in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)
An AIN diagnosis in patients with DM is associated with 56% lower likelihood of prior metformin use. This relationship suggests that metformin could potentially play a protective role against AIN. Prospective studies in non-diabetic patients are warranted to examine these findings further.
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