Salivary epigenetic biomarkers as predictors of emerging childhood obesity.

Amanda RushingEvan C SommerShilin ZhaoEli K Po'eShari L Barkin

Published in: BMC medical genetics (2020)

Saliva offers a non-invasive means of DNA collection and epigenetic analysis. Our proof of principle study provides sound empirical evidence supporting DNA methylation in salivary tissue as a potential predictor of subsequent childhood obesity for Hispanic children. NFR1 could be a target for further exploration of obesity in this population.

Keyphrases

dna methylation
gene expression
genome wide
insulin resistance
metabolic syndrome
young adults
weight loss
circulating tumor
single molecule
weight gain
physical activity
high fat diet induced
copy number
adipose tissue
nucleic acid