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Reappraisal of the genetic heterogeneity of sessile serrated adenoma/polyp.

Hourin ChoTaiki HashimotoHiroshi YoshidaHirokazu TaniguchiReiko OgawaTaisuke MoriNobuyoshi HiraokaYutaka SaitoShigeki Sekine
Published in: Histopathology (2018)
The present study confirmed the common presence of the BRAF V600E mutation in SSA/Ps, but also demonstrated a degree of molecular heterogeneity of SSA/Ps. SSA/Ps with and without the BRAF V600E mutation showed slightly different but overlapping histological and molecular features.
Keyphrases
  • single cell
  • metastatic colorectal cancer
  • single molecule
  • gene expression
  • dna methylation