Antibodies, boosters, and optimizing SARS-CoV-2 vaccines for transplantation: A call for more research.

Michael G Ison Emily A BlumbergNatasha HalasaDaniel R Kaul Nicole M TheodoropoulosCameron R Wolfe

Published in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons (2021)

Despite emerging data suggesting reduced antibody responses among solid organ transplant recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.

Keyphrases

sars cov
respiratory syndrome coronavirus
case control
immune response
electronic health record
early onset
stem cells
big data
machine learning
bone marrow
data analysis