Evaluation of circulating serum cathelicidin levels as a potential biomarker to discriminate between active and latent tuberculosis in Uganda.
Ester Lilian AcenDavid Patrick KateeteWilliam WorodriaRonald OlumMoses L JolobaMudarshiru BbuyeIrene Andia BiraroPublished in: PloS one (2022)
Significantly higher LL-37 levels were observed among active tuberculosis patients than those without tuberculosis infection and were, therefore able to discriminate between active tuberculosis and other tuberculosis infectious states, especially with no tuberculosis. Further assessment of this biomarker as a screening tool to exclude tuberculosis is required.