miR-128 regulated the proliferation and autophagy in porcine adipose-derived stem cells through targeting the JNK signaling pathway.
Pengfei GaoHaizhen WangJuan LiuYiqi WuWei HeiZhiqiang HeChunbo CaiXiaohong GuoGuoqing CaoBugao LiPublished in: Journal of receptor and signal transduction research (2020)
It is demonstrated that the miR-128-JNK signaling pathway is a potential therapeutic target for the treatment of obesity.
Keyphrases
- signaling pathway
- cell proliferation
- pi k akt
- long non coding rna
- induced apoptosis
- long noncoding rna
- epithelial mesenchymal transition
- insulin resistance
- metabolic syndrome
- cell death
- transcription factor
- weight gain
- oxidative stress
- high fat diet induced
- skeletal muscle
- wound healing
- physical activity
- replacement therapy
- climate change