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Thromboxane-prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats.

David LagierDavid TononPhilippe GarrigueBenjamin GuilletLaura GiacominoJean-Charles MartinMarie-Christine AlessiNicolas BruderLionel J Velly
Published in: Critical care (London, England) (2019)
Based on in vivo nanoscale imaging, we demonstrated that TBN protected against blood-brain barrier disruption, exerted an anti-apoptotic effect and improved cerebral perfusion. Thus, TP receptor antagonists showed promising results in treating post-haemorrhage neurovascular events.
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