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Lymphatic Vessels in the Inner Ear of Patients With Meniere Disease: A Novel Pathological Finding.

Daogong ZhangXiaofei LiYafeng LvYongdong SongLigang KongBoqin LiJinfeng ZhengNicolas Pérez-FernándezZhaomin FanHai-Bo Wang
Published in: OTO open (2024)
This is the first report of lymphatic vessels in the human inner ear, and this pathological structure is a completely new discovery. The lymphatic vessels may develop due to inflammation or decompensation of pressure in the inner ear, suggesting that the inner ear can reactively form lymphatic vessels in some inflammation and fluid flow-dependent pathological conditions. The current findings help in improving our understanding of the pathogenesis of Meniere disease.
Keyphrases
  • lymph node
  • oxidative stress
  • endothelial cells
  • small molecule
  • high throughput
  • single cell