Morphological and Functional Changes in the Peritumoral Adipose Tissue of Colorectal Cancer Patients.

Elena ZoicoVanni RizzattiElena DarraSimona Luciana BuduiGuido FranceschettiFabrizio VinanteCorrado PedrazzaniAlfredo GuglielmiGiovanni De ManzoniGloria MazzaliAndrea Petronio RossiFrancesco FantinMauro Zamboni

Published in: Obesity (Silver Spring, Md.) (2018)

This study reveals important morphological and functional changes in the AT surrounding the tumor as an increase in lipolysis and in adiponectin-producing adipocytes, preferentially infiltrated by a macrophage subset, with prevalent reparative inflammatory response.

Keyphrases

adipose tissue
insulin resistance
inflammatory response
high fat diet
metabolic syndrome
lipopolysaccharide induced
type diabetes
lps induced
immune response