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Two new steroid sulfates from a cheilostome bryozoan, Calyptotheca sp.

Sona Rani RoyAlisa MineiPeni AhmadiIdam HermawanViqqi KurniandaMatthew H DickJunichi Tanaka
Published in: Natural product research (2020)
Two new steroid sulfates 1 and 2 were obtained from a lipophilic extract of an undescribed bryozoan species in the genus Calyptotheca. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and chemical modifications. Steroids 1 and 2 exhibited moderate cytotoxicity at IC50 54 and 30 µM, respectively, against NBT-T2 cells.
Keyphrases
  • molecular docking
  • oxidative stress
  • high intensity
  • anti inflammatory